>About KNUP > professor
 
Jeong Ah Kim
Office Phone Number : +82-53-950-8574
Fax Number : +82-53-950-8557
Office : 403-1
Homepage : http://pharmacy.knu.ac.kr/jkim/
E-mail : jkim6923@knu.ac.kr
Major in Graduate School : Natural Product Chemistry, Pharmacognosy
 
Education Bachelor’s Degree: College of Pharmacy, Yeungnam University, 1999

Master’s Degree: College of Pharmacy, Yeungnam University, 2001

Doctor of Philosophy: College of Pharmacy, Yeungnam University, 2004
Major Experience 1) Researcher: Institute for Drug Research, Yeungnam University, 2004.8-2006.8

2) Postdoctoral Researcher: College of Pharmacy, The Ohio State University, 2006.5-2009.2

3) Research Professor: Institute of Drug Research & Development, Chungnam National University, 2009.5-2012.2
Research area
of interest
Topic #1: Isolation and Structure Elucidation of Natural Compounds from Medicinal Plants
Activity-guided fractionation by using various column chromatographies
Structure elucidation of natural compounds by using various spectroscopic methods (NMR, MS, UV, IR etc)
Analysis of organic compounds from natural sources by HPLC & GC

Topic #2: Pharmacological Evaluation of Natural Products
Anti-inflammatory activity
Anti-melanogenesis and anti-oxidant activity
Anti-cancer effect

Topic #3: Development and Standardization of Oriental Medicines
Development of validation techniques for the standardized natural product preparations
Development of new chromatographic methods for extraction and purification of natural products

Topic #4: Development of New Drugs, Botanical Dietary Supplements and Functional Cosmetics from Natural Sources
Major Publication
within 3 years
1.   Kim JA, Son JH, Yang SY, Song SB, Song GY, Kim YH. A new lupane-type triterpene from the seeds of Panax ginseng with its inhibition of NF-κB. Arch Pharm Res 35: 647-651 (2012) April.

2.   Kim JA, Yang SY, Kang S, and Kim YH. Cyclooxgenase Inhibitory Components from Portulaca oleracea. Nat Prod Sci 18: 22-25 (2012) March.

3.   Kim JA, Yang SY, Kang S, and Kim YH. Verticilloside, a new daucosteryl derivative from the seeds of Malva verticillata. Nat Prod Sci 17: 350-353 (2011) December.

4.   Kim JA, Jung YS, Kim MY, Yang SY, Lee S, and Kim YH. Protective effect of components isolated from Lindera erythrocarpa against oxidative stress-induced apoptosis of H9c2 cardiomyocytes. Phytother Res 25: 1612-1617 (2011) November.

5.   Kim JA, Lau E, Tay D, and Carcache-Blanco JE. Antioxidant and NF-κB inhibitory constituents isolated from Morchella esculenta. Nat Prod Res 25: 1412-1417 (2011) September.

6.   Liang C, Ding Y, Kim JA, Yang SY, Boo HJ, Kang HK, Cuong MN, and Kim YH. Polyacetylenes from Panax stipuleanatus and their cytotoxic effects on human cancer cells. Bull Korean Chem Soc 32: 3513-3516 (2011) September.

7.   Ding Y, Kim JA, Yang SY, Kim WK, Lee SH, Jang HD, and Kim YH. Antioxidative sesquiterpenes from Artemisia iwayomogi. Bull Korean Chem Soc 32: 3493-3496 (2011) September.

8.   Kim JA, Song SB, Yang SY, and Kim YH. Components from the steamed leaves of Acanthopanax koreanum and their effects of PPAR activity in HepG2 cells. Nat Pod Commun 6: 1233-1236 (2011) September.

9.   Kim JA, Yang SY, Song SB, and Kim YH. Effects of impressic acid from Acanthopanax koreanum on NFκB and PPARγ activities. Arch Pharm Res 34: 1347-1351 (2011) August.

10.Kim JA, Son JH, Yang SY, and Kim YH. Isoconiferoside, a new phenolic glucoside from seeds of Panax ginseng. Molecules 16: 6577-6581 (2011) August.

11.Kim JA, Yang SY, Wamiru A, McMahon BJ, Le Grice FJS, Beutler AJ, and Kim YH. New monoterpene glycosides and phenolic compounds from Distylium racemosum, and their inhibitory activity against ribonuclease H. Bioorg Med Chem Lett 21: 2840-2844 (2011) May.

12.Lee HS, Hwang IH, Kim JA, Choi JY, Jang TS, Osada H, Ahn JS, Na MK, and Lee SH. Isolation of protein tyrosine phosphatase 1B inhibitory constituents from the sclerotia of Polyporus umbellatus Fries. Bull Korean Chem Soc 32: 697-700 (2011) February.

13.Nhiem NX, Kim KC, Kim AD, Hyun JW, Kang HK, Kiem PV, Minh CV, Thu V K, Tai BH, Kim JA, and Kim YH. Phenylpropanoids from the leaves of Acanthopanax koreanum and their antioxidant activity. J Asian Nat Prod Res 13: 56-61 (2011) January.

14.Liang C, Ding Y, Tung NH, Kim JA, Boo HJ, Kang HK, Cuong NM, and Kim YH. Oleanane-type triterpenoids from Panax stipuleanatus and their anticancer activities. Bioorg Med Chem Lett 20: 7110-7115 (2010) December.

15.Kim HJ, Hong JM, Jung JW, Kim TH, Kim JA, Kim YH, and Kim SY. Gymnasterkoreayne F inhibits osteoclast formation by suppressing NFATc1 and DC-STAMP expression. Int Immunopharmacol 10: 1440-1447 (2010) November.

16.Tung NH, Yang SY, Kim JA, Song GY, and Kim YH. Dammarane-type saponins from the black ginseng. Bull Korean Chem Soc 31: 3423-3426 (2010) November.

17.Kim JA, Yang SY, Koo JE, Koh YS, and Kim YH. Lupane-type triterpenoids from the steamed leaves of Acanthopanax koreanum and their inhibitory effects on the LPS-stimulated proinflammatory cytokine production in bone marrow-derived dendritic cells. Bioorg Med Chem Lett 20: 6703-6707 (2010) November.

18.Choi JG, Kang OH, Chae HS, Obiang-Obounou B, Lee YS, Oh YC, Kim MS, Shin DW, Kim JA, Kim YH, and Kwon DY. Antibacterial activity of Hylomecon hylomeconoides against methicillin-resistant Staphylococcus aureus. Appl Biochem Biotechnol 160: 2467-2474 (2010) November.

19.Kim NH, Kim KY, Kim JA, Kim YH, Kang IC, Kim HM, and Jeong HJ. Immune-enhancing effect of Acanthopanax Koreanum and its component, Eleutheroside E on the protein-energy malnourished C57bl/6 mice. Orient Pharm Exp Med 10: 191-199 (2010) September.

20.Ding Y, Liang C, Tung HN, Choi EM, Kim JA, and Kim YH. Chemical constituents from Acer mandshuricum and their effects on the function of osteoblastic MC3T3-E1 cells. Bull Korean Chem Soc 31: 929-933 (2010) September.

21.Kim JA, Lau KE, Pan L, and Carcache-Blanco JE. NF-κB inhibitors from Brucea javanica exhibiting intracellular effects on reactive oxygen species. Anticancer Res 30: 3295-300 (2010) September.

22.Ding Y, Liang C, Yang SY, Ra JC, Choi EM, Kim JA, and Kim YH. Phenolic compounds from Artemisia iwayomogi and their effects on osteoblastic MC3T3-E1 cells. Biol Pharm Bull 33: 1448-53 (2010) August.

23.Tung NH, Song SB, Song GY, Kim JA, Koo JE, Kang HK, Koh YS, and Kim YH. Inhibitory effect of ginsenosides from ginseng leaves and flowers on the LPS-stimulated IL-12 production in bone marrow-derived dendritic cells. Food Sci Biotechnol 19: 1119-1122 (2010) August.

24.Tung NH, Cho K, Kim JA, Song GY, and Kim YH. Dammarane-type glycosides from the steamed flower-buds of Panax ginseng. Bull Korean Chem Soc 31: 1381-1384 (2010) May.

25.Tai BH, Huyen VT, Huong TT, Nhiem NX, Choi EM, Kim JA, Long PQ, Cuong NM, and Kim YH. New pyrano-pyrone from Goniothalamus tamirensis enhances the proliferation and differentiation of osteoblastic MC3T3-E1 cells. Chem Pharm Bull 58: 521-525 (2010) April.

26.Kim DC, Kim JA, Min BS, Jang TS, Na MK, and Lee SH. Guaiane sesquiterpenoids isolated from the fruits of Torilis japonica and their cytotoxic activity. Helv Chim Acta 93: 692-697 (2010) April.

27.Ding Y, Liang C, Kim JH, Lee YM, Hyun JH, Kang HK, Kim JA, Min BS, and Kim YH. Triterpene compounds isolated from Acer mandshuricum and their anti-inflammatory activity. Bioorg Med Chem Lett 20: 1528-1531 (2010) March.

28.Tung NH, Kwon HJ, Kim JH, Ra JC, Kim JA, and Kim YH. An anti-influenza component of the bark of Alnus japonica. Arch Pharm Res 33: 363-367 (2010) March.

29.Tung NH, Son JH, Cho K, Kim JA, Hyun J H, Kang HK, Song GY, Park CJ, and Kim YH. Phenolic components from the leaves of Panax ginseng and their effects on HL-60 human leukemia cells. Food Sci Biotechnol 19: 271-274 (2010) February.

30.Tung NH, Kwon HJ, Kim JH, Ra JC, Ding Y, Kim JA, and Kim YH. Anti-influenza diarylheptanoids from the bark of Alnus japonica. Bioorg Med Chem Lett 20: 1000-1003 (2010) February.

31.Tung NH, Song GY, Kim JA, Hyun JH, Kang HK, and Kim YH. Dammarane-type saponins from the flower buds of Panax ginseng and their effects on human leukemia cells. Bioorg Med Chem Lett 20: 309-314 (2010) January.

32.Park SH, Nhiem NX, Kiem PV, Choi EM, Kim JA, and Kim YH. A new norlupane triterpene from the leaves of Acanthopanax koreanum increases the differentiation of osteoblastic MC3T3-E1 cells. Arch Pharm Res 33: 75-80 (2010) January.